Aromatic benzotriazole amides--synthesis and biological evaluation.
نویسندگان
چکیده
Four derivatives of benzotriazole-5-carboxylic acid were synthesized as potential UV-light dependent DNA cleaving agent. The effect of these compounds on phiX174 RF1 phage DNA and pBR322 plasmid DNA was investigated with and without UV exposure. It has been found that the two compounds exert the influence on topological forms of DNA.
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ورودعنوان ژورنال:
- Acta poloniae pharmaceutica
دوره 62 1 شماره
صفحات -
تاریخ انتشار 2005